The most important international routes are:
The Karakoram Highway leading across the whole northern Pakistan to China.
Highway N40 use tourists traveling to Pakistan on land from Iran, or rather from Europe, leading through the deserts of Balochistan.
The road from Lahore to Amritsar in India.
Now little used road Highway N5 from Islamabad to Kabul in Afghanistan.
To the remote mountain villages or treks starting bases run jeeps. But their drivers can collect several times higher fare from tourists than they want from the locals, especially in directions from where you start mountain treks or climbing expeditions. It is certainly necessary to haggle about the price.